Welcome to the edurant patients and caregivers website like most people, you probably have questions about hiv and how its treated. Tivicay is used to treat hiv human immunodeficiency virus infection in adults, adolescents and children over 6 years old, who weigh at least 15 kg. Tivicay as part of juluca is used as a medication to switch to for people with undetectable viral loads on their current regimen for at least six months. If the patient misses a dose of tivicay, the patient should take tivicay as. Interactions between antiepileptics and antiretrovirals. Elvitegravir auc decreased 1520% if given simultaneously with boosted pi, but. Page 2 of 21 full prescribing information 1 indications and usage 1. Posttreatment acute exacerbation of hepatitis b and risk of drug resistance with use of truvada for hiv1 preexposure prophylaxis prep in. Tivicay contains the active ingredient dolutegravir. Tivicay comes in tablet form in the following strengths. Must be taken with ritonavir and food and should not be used in pediatric patients who weigh less than 5 kg. Tivicay tablets, 25 mg, are pale yellow, round, filmcoated, biconvex tablets debossed with sv 572 on one side and 25 on the other side.
Never shake the vial butgently tap the fuzeon vial with fingertip for 10 seconds to start dissolving the powder. Truvada emtricitabine and tenofovir disoproxil fumarate tablets, for oral use initial u. Tivicay is particularly useful when drug interactions are a concern with the hiv protease inhibitor pi drugs. If certain ugt1a or cyp3a inducers are coadministered, then adjust the weightbased dose of tivicay to twice daily. Tivicay must be used in combination with other hiv drugs.
Prezista darunavir patients and caregivers homepage. Tivicay tablets, 25 mg, are pale yellow, round, filmcoated. Dmannitol, microcrystalline cellulose, povidone k2932, sodium starch glycolate, and sodium stearyl fumarate. This leaflet is part iii of a threepart product monograph published. Isentressand isentresshd areindicated in combination with other antiretroviralagents for the treatment of human immunodeficiency virus hiv1 infectionin adultpatients. Turn the vial upside down and draw 1mlof the sterile water into the syringe then remove the needle and syringe from the vial. Tivicay dolutegravir is an fda approved prescription hiv1 medication. A safe and effective dose of kaletra oral solution in this. Prezista should not be used in children under 3 years of age. In vitro, dolutegravir inhibited the renal organic cation transporters. Kaletra oral solution should not be used in preterm neonates in the immediate postnatal period because of possible toxicities. Tivicay is a human immunodeficiency virus type 1 hiv1 integrase strand transfer inhibitor insti indicated in combination with. Sabril can cause permanent bilateral concentric visual field constriction, including tunnel vision that can result in disability.
Insert sterile syringe needle into the vial through the center of the stopper. Take dolutegravir according to your health care providers instructions. Information for the patient tivicay 10 mg filmcoated tablets tivicay 25 mg filmcoated tablets tivicay 50 mg filmcoated tablets dolutegravir read all of this leaflet carefully before you start taking this medicine because it contains important information for you. Tivicay is an hiv medication in a category called integrase inhibitors. Must be taken with ritonavir and food and should not be used in. Highlights of prescribing information these highlights do not include all the information needed to use tivicay safely and effectively. Administer tivicay 2 hours before or 6 hours after taking antacids, polyvalent cationcontaining products or laxatives. Alternatively, oral calcium and iron supplements including multivitamins containing calcium or iron can. Dolutegravir tivicay package insert daids regulatory support.
These highlights do not include all the information needed to use tamiflu safely and effectively. Read the patient information leaflet if available from your pharmacist before you start taking dolutegravir and each time you get a refill. Risk increases with increasing dose and cumulative exposure, but there is no dose or exposure to sabril known to be free of risk of vision loss 5. Tivicay hiv1 treatment powered by dolutegravir at the. Perform pregnancy testing before initiation of tivicay in adolescents and adults of childbearing potential see warnings and precautions 5. Dolutegravir belongs to a group of antiretroviral medicines called integrase inhibitors inis. Tivicay is a prescription hiv1 medicine that is used with other antiretroviral medicines to treat human immunodeficiency virus1 hiv1 infection. Highlights of prescribing information coadministration with. Highlights of prescribing information nss are frequent nss. Inject the sterile water slowly, so that it drips down the side of the vial into the fuzeon powder. Screen for the hlab5701 allele prior to initiating therapy with triumeq see boxed warning, warnings and precautions 5. Highlights of prescribing information these highlights do not.
Store and dispense the 10mg tablets in the original package, protect from moisture, and keep the bottle tightly closed. These highlights do not include all the information needed to. Tivicay is used with other antiviral medications to treat hiv, the virus that can. Juluca is a prescription medicine that is used without other antiretroviral medicines to treat human immunodeficiency virus1 hiv1 infection in adults to replace their current antihiv1 medicines. Tivicay dolutegravir tablets, for oral use initial u. Tivicay dolutegravir is an antiviral medicine that prevents human immunodeficiency virus hiv from multiplying in your body. Biktarvy combines the descovy ftctaf backbone with bictegravir, a novel and unboosted insti, for a powerful str with a high barrier to resistance. Highlights of prescribing information preexisting conduction. Dolutegravir dtg, sold under the brand name tivicay, is an antiretroviral medication used, together with other medication, to treat hivaids. Prezista darunavir is a prescription hiv1 human immunodeficiency virus type1 medicine used with norvir ritonavir and other antiretroviral medicines to treat hiv1 infection in adults. Our tivicay dolutegravir side effects drug center provides a comprehensive view of available drug information on the potential side effects when taking this medication. This site was created to answer some of your questions and help you learn about edurant rilpivirine 25mg tablets, a prescription medicine used with other arv medicines in patients who have never taken hiv medicines before and who have an amount of. Tamiflu reduce to 30oseltamivir phosphate capsules, for oral use.
In some cases, sabril may also decrease visual acuity 5. Reportsonantenatalhivtestinginirelandfile,15285,en. Intelence is a prescription medicine that is used in combination with other antiretroviral medicines to treat human immunodeficiency virus1 hiv1 infection in adults and children 2 years of age and older, who have taken hiv1 medicines in the past. Klibanov is an associate professor of pharmacy at wingate university, wingate, n.
Administer tivicay 2 hours before or 6 hours after taking medications containing polyvalent cations. Mar 09, 2020 to learn more about possible side effects of dolutegravir, read the drug label or package insert or talk to your health care provider or pharmacist. It is used with other hiv1 medicines to lower viral load and increase cd4 count. It may also be used, as part of post exposure prophylaxis, to prevent hiv infection following potential exposure. Tivicay dolutegravir tablets for oral use initial u. Hiv is the virus that causes aids acquired immune deficiency syndrome. When possible, interrupt therapy with brilinta for fivedays prior to surgery that has a major risk of bleeding.
Dolutegravir tivicay treatment national hiv curriculum. About juluca for hiv treatment juluca dolutegravir and. Each filmcoated tablet of tivicay for oral administration contains 10. Elvitegravir auc decreased 1520% if given simultaneously with boosted pi, but antacid was separated by 2 hours.
Tivicay is used with other antiviral medications to treat hiv, the virus that can cause the acquired immunodeficiency syndrome aids. Highlights of prescribing information because triumeq is a. Dosing recommendations for tivicay in adult patients. Hiv1 is the virus that causes acquired immune deficiency syndrome aids. Dolutegravir fda label tablet film coated aidsinfo. Isentress is indicated in combination with other antiretroviral agents for the treatment of hiv1 infection in pediatric patientsweighing at least 2 kg.
For those switching to dolutegravir plus rilpivirine must be taken with a meal. Food and drug administration for use by people living with hiv in august 20. The recommended dose of tivicay in pediatric patients weighing at least 30 kg is provided in table 2. Insert the syringe with sterile water into the fuzeon vial at an angle. It is not known if tivicay is safe and effective in children under 12 years of age or who weigh less than 88 pounds. Truvada tenofoviremtricitabine one blue tablet daily, plus tivicay 50mg. No treatmentemergent resistanceincluding insti and nrti resistancewas associated with biktarvy in treatmentnaive clinical trials through week 144 and in virologically suppressed clinical trials through week 48. After exposure to hiv through sexual contact or injecting drug use. Highlights of prescribing information recommended dosage in.
Hiv1 is the virus that causes aids acquired immune deficiency syndrome. Tivicay is a human immunodeficiency virus type 1 hiv1 integrase strand. Dolutegravir tivicay for hiv infection request pdf. Tivicay, in combination with other antiretroviral agents, is indicated for the treatment of human. You can report side effects to fda at 1800fda1088 18003321088 or online. Kaletra oral solution should not be used in preterm neonates in the immediate. Reyataz capsule dosage is based on body weight not to exceed the adult doseand must be taken with food.
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